ICD-10 Code D57.8 – Other sickle-cell disorders (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other sickle-cell disorders is D57.8.
2026 ICD-10-CM Diagnosis Code D57.8 – Other sickle-cell disorders

What it is

D57.8 identifies sickle-cell disorders that do not fit a more specific ICD-10 category. Use it for documented sickling conditions when the record does not support a narrower code.

Clinical signs

Clinical features vary; refer to documentation. Commonly reported findings in sickle-cell disorders include anemia, pain episodes, jaundice, and other complications related to abnormal red blood cell shape.

When to use this code

Use this code when the clinician documents an “other” sickle-cell disorder or a sickling condition without a more specific subtype. It is also appropriate when the chart confirms sickle-cell disease but does not identify the exact variant. Check documentation before assigning it.

Do not use for

Do not use D57.8 when the record supports a specific sickle-cell diagnosis with its own code, such as a clearly documented subtype. Do not use it for sickle-cell trait or unrelated anemia.

Coding tip

Choose the most specific sickle-cell code available; reserve D57.8 for nonspecific or other documented sickle-cell disorders.

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