ICD-10 Code D57 – Sickle-cell disorders (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57 – Sickle-cell disorders
What it is
D57 identifies sickle-cell disorders, a group of inherited hemoglobin conditions that can cause red blood cells to become abnormally shaped. Use it when the record documents sickle-cell disease, sickle-cell anemia, or another specified sickling disorder.
Clinical signs
Clinical features vary; refer to documentation. Commonly recorded findings include chronic anemia, recurrent pain episodes, jaundice, and complications from vaso-occlusion or hemolysis.
When to use this code
Use D57 when the clinician documents a sickle-cell disorder without a more specific subtype in the record. It also fits encounters for established sickle-cell disease with related manifestations already documented. If the note names a specific sickle-cell variant, code that more precise option instead.
Do not use for
Do not use D57 for trait or carrier status without disease. Also avoid it when the chart clearly identifies a different hemoglobinopathy or a more specific sickle-cell code.
Coding tip
Check documentation for the exact sickle-cell type and any associated complications before assigning the code.