ICD-10 Code D57.0 – Hb-SS disease with crisis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.0 – Hb-SS disease with crisis
What it is
D57.0 identifies sickle cell anemia due to Hb-SS with an active crisis. Use it when the record shows Hb-SS disease and a current acute sickling episode.
Clinical signs
Clinical features vary; refer to documentation. Commonly documented findings include acute pain episodes, anemia-related symptoms, and complications such as vaso-occlusion or acute sickle crisis.
When to use this code
Use this code when the provider documents Hb-SS disease with crisis, sickle cell crisis, or an acute painful episode tied to Hb-SS. It fits encounters for active crisis management or evaluation. If the crisis type is specified, code the documented type when supported by the record.
Do not use for
Do not use D57.0 for Hb-SS disease without crisis, trait, or other sickle cell genotypes. Check documentation if the note only states anemia or a history of sickle cell disease.
Coding tip
Link the code to the provider’s exact wording for Hb-SS and crisis, and do not assume an acute crisis without clear documentation.