ICD-10 Code C49.22 – Malignant neoplasm of connective and soft tissue of left lower limb, including hip (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Malignant neoplasm of connective and soft tissue of left lower limb, including hip is C49.22.
2026 ICD-10-CM Diagnosis Code C49.22 – Malignant neoplasm of connective and soft tissue of left lower limb, including hip

What it is

This code identifies a malignant tumor arising in the soft tissues or connective tissues of the left lower limb, including the hip. Use it when the record specifies the left side and the site is not a bone or joint.

Clinical signs

Clinical features vary; refer to documentation. Soft tissue sarcomas may present as a growing mass, pain, swelling, or limited movement when near joints.

When to use this code

Use C49.22 when the provider documents a malignant neoplasm of connective or soft tissue in the left leg or hip region. It is appropriate for confirmed primary tumors and for site-specific coding when laterality is clearly stated.

Code from the pathology, imaging, or operative report when the anatomic site is documented. If the record only says “soft tissue sarcoma” without laterality, check documentation before assigning this code.

Do not use for

Do not use this code for malignant bone tumors, benign soft tissue masses, or unspecified limb laterality. Check documentation if the lesion is metastatic, recurrent, or described only as a mass.

Coding tip

Confirm both the tissue type and the left-sided location before coding; laterality matters for this diagnosis.

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