ICD-10 Code D57.1 – Sickle-cell disease without crisis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.1 – Sickle-cell disease without crisis
What it is
D57.1 identifies sickle-cell disease when the patient has the disorder but is not currently having an acute crisis. Use it for documented sickling disease without an active pain episode or other crisis.
Clinical signs
Clinical features vary; refer to documentation. Patients may have chronic hemolytic anemia, fatigue, jaundice, or a known history of sickle-cell disease, but no current crisis is documented.
When to use this code
Use this code when the provider documents sickle-cell disease and specifically states “without crisis,” “no crisis,” or similar wording. It also fits follow-up visits for established disease when the encounter is not for an acute sickling event. Check documentation if the record mentions pain or complications.
Do not use for
Do not use D57.1 if an acute sickle-cell crisis is documented, or if the record specifies a different sickle-cell subtype. Do not assume “sickle-cell trait” or an unspecified hemoglobinopathy is the same diagnosis.
Coding tip
Code the crisis status exactly as documented, and query the provider if the note does not clearly state whether a crisis is present.