ICD-10 Code D57.03 – Hb-SS disease with cerebral vascular involvement (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.03 – Hb-SS disease with cerebral vascular involvement
What it is
This code identifies sickle cell anemia, Hb-SS type, with cerebral vascular involvement. Use it when the record shows a cerebrovascular complication linked to sickling, such as stroke or other brain vessel involvement.
Clinical signs
Findings may include acute neurologic deficits, altered speech, weakness, facial droop, or other evidence of cerebral ischemia. Clinical features vary; refer to documentation.
When to use this code
Use D57.03 when the provider documents Hb-SS disease and a cerebral vascular complication, including an ischemic or hemorrhagic cerebrovascular event attributed to sickle cell disease. Apply it when the chart clearly links the brain vascular involvement to the Hb-SS condition. Check documentation if the neurologic problem is described without that connection.
Do not use for
Do not use this code for sickle cell disease without cerebral vascular involvement, or for neurologic symptoms that are not documented as cerebrovascular. If the record only says “history of stroke,” check documentation.
Coding tip
Verify both the Hb-SS diagnosis and the cerebrovascular complication are explicitly documented before assigning D57.03.