ICD-10 Code D57.218 – Sickle-cell/Hb-C disease with crisis with other specified complication (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Sickle-cell/Hb-C disease with crisis with other specified complication is D57.218.
2026 ICD-10-CM Diagnosis Code D57.218 – Sickle-cell/Hb-C disease with crisis with other specified complication

What it is

This code identifies sickle-cell/Hb-C disease when the patient is having a crisis and the complication is documented as other specified. Use it for a sickling disorder involving hemoglobin S and hemoglobin C, with a named complication not captured by a more specific code.

Clinical signs

Clinical features vary; refer to documentation. Typical crisis findings may include acute pain, anemia-related symptoms, or other sickle-cell complications, but the record must support the Hb-C disease and the specified crisis complication.

When to use this code

Use this code when the provider documents sickle-cell/Hb-C disease with crisis and also names an additional complication that is not classified elsewhere in the sickle-cell code set. It is appropriate only when the chart clearly links the crisis to the Hb-C disorder. If the complication is described more specifically, choose the more exact code.

Do not use for

Do not use this code for uncomplicated sickle-cell/Hb-C disease, or when the record does not mention a crisis. Do not use it if another sickle-cell complication code fits better; check documentation.

Coding tip

Confirm both elements in the note: Hb-C disease and the “other specified complication” during crisis.

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