ICD-10 Code D57.214 – Sickle-cell/Hb-C disease with dactylitis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.214 – Sickle-cell/Hb-C disease with dactylitis
What it is
D57.214 identifies sickle-cell/Hb-C disease when it presents with dactylitis, a painful swelling of the hands or feet. Use it for documented sickle-cell hemoglobin C disease with this specific complication.
Clinical signs
Typical findings include acute pain, swelling, and tenderness of the fingers, hands, toes, or feet. Clinical features vary; refer to documentation for confirmed hemoglobin C disease and dactylitis.
When to use this code
Use this code when the record clearly states sickle-cell/Hb-C disease and documents dactylitis as a current or associated manifestation. It is appropriate when the provider links the swelling episode to the hemoglobinopathy. Check documentation if the note only says hand-foot pain without a diagnosis.
Do not use for
Do not use it for sickle-cell disease without Hb-C involvement, or for dactylitis from another cause. Do not assign it when the chart lacks confirmation of both the genotype and the dactylitis diagnosis.
Coding tip
Confirm both the specific sickle-cell/Hb-C diagnosis and the documented dactylitis before assigning D57.214.