ICD-10 Code D57.414 – Sickle-cell thalassemia, unspecified, with dactylitis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.414 – Sickle-cell thalassemia, unspecified, with dactylitis
What it is
D57.414 identifies sickle-cell thalassemia, unspecified, when the patient has dactylitis. It combines a sickling hemoglobin disorder with painful swelling of the hands or feet.
Clinical signs
Typical findings include tender, swollen digits or extremities, especially in children, with pain consistent with vaso-occlusive involvement. Clinical features vary; refer to documentation.
When to use this code
Use this code when the record clearly documents sickle-cell thalassemia and dactylitis at the same encounter. You may use it for confirmed painful swelling of the hands or feet linked to the sickle-cell disorder. Check documentation if the genotype or complication is not stated.
Do not use for
Do not use this code for sickle-cell disease without thalassemia, or for dactylitis from another cause. If the chart does not specify dactylitis, choose the more accurate sickle-cell code.
Coding tip
Verify both the thalassemia type and the presence of dactylitis before assigning D57.414.