ICD-10 Code D59.39 – Other hemolytic-uremic syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D59.39 – Other hemolytic-uremic syndrome
What it is
D59.39 identifies hemolytic-uremic syndrome that does not fit a more specific category. It is used for a thrombotic microangiopathy with hemolysis, low platelets, and kidney injury when documentation supports this diagnosis.
Clinical signs
Clinical features vary; refer to documentation. Typical findings include evidence of hemolytic anemia, thrombocytopenia, and acute renal impairment, often with fatigue, pallor, bruising, or reduced urine output.
When to use this code
Use D59.39 when the provider documents hemolytic-uremic syndrome and does not specify a more exact subtype. Code it from discharge summaries, consult notes, or problem lists when the diagnosis is established and supported by the record.
Choose this code for “other” or unspecified HUS presentations that are not clearly linked to a defined cause in the documentation. Check documentation if the record suggests another thrombotic microangiopathy.
Do not use for
Do not use this code for a clearly documented specific HUS type when a more precise code is available. Do not assign it if the record only mentions hemolysis or kidney injury without a documented HUS diagnosis.
Coding tip
Confirm the provider’s exact wording and code the most specific HUS diagnosis supported by the chart.