ICD-10 Code D59.2 – Drug-induced nonautoimmune hemolytic anemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D59.2 – Drug-induced nonautoimmune hemolytic anemia
What it is
D59.2 identifies hemolytic anemia caused by a drug, where red blood cells are destroyed without an autoimmune mechanism. Use it when documentation links the anemia directly to medication exposure.
Clinical signs
Clinical features vary; refer to documentation. Typical findings may include anemia symptoms and evidence of hemolysis, with the clinician noting a drug-related, nonautoimmune cause.
When to use this code
Use D59.2 when the record clearly states drug-induced nonautoimmune hemolytic anemia. It fits cases where a medication is identified as the cause and the provider distinguishes it from autoimmune hemolysis. Check documentation if the cause is uncertain or only suspected.
Do not use for
Do not use this code for autoimmune hemolytic anemia or hemolysis not linked to a drug. If the chart only says “anemia” or “hemolysis” without a medication cause, code more specifically from the documentation.
Coding tip
Look for explicit provider wording connecting the anemia to a drug and confirming it is nonautoimmune.