ICD-10 Code D59 – Acquired Hemolytic Anemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D59 – Acquired hemolytic anemia
What it is
D59 identifies acquired hemolytic anemia, a condition in which red blood cells are destroyed faster than the body can replace them. It is used when the anemia is not congenital and the cause is acquired.
Clinical signs
Typical findings include anemia-related fatigue, pallor, and shortness of breath, with evidence of hemolysis in clinical evaluation. Clinical features vary; refer to documentation.
When to use this code
Use D59 when the record clearly states acquired hemolytic anemia without a more specific subtype. This code is appropriate for confirmed hemolytic anemia due to an acquired process, including cases where the provider documents hemolysis as the primary diagnosis. If the cause is specified, code that documented etiology when instructed by the record.
Do not use for
Do not use D59 for congenital hemolytic anemias or for anemia without documented hemolysis. Check documentation when the chart only notes low hemoglobin or an unspecified anemia.
Coding tip
Look for the provider’s exact wording on acquired hemolysis, and code the most specific documented subtype when available.