ICD-10 Code D59.13 – Mixed type autoimmune hemolytic anemia (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Mixed type autoimmune hemolytic anemia is D59.13.
2026 ICD-10-CM Diagnosis Code D59.13 – Mixed type autoimmune hemolytic anemia

What it is

This code identifies mixed type autoimmune hemolytic anemia, a condition in which both warm and cold autoantibodies contribute to red blood cell destruction. Use it when documentation specifically states this mixed autoimmune mechanism.

Clinical signs

Clinical features may include anemia-related fatigue, pallor, jaundice, and evidence of hemolysis. Serologic testing may show both warm and cold antibody activity; if unclear, check documentation.

When to use this code

Use D59.13 when the provider documents mixed type autoimmune hemolytic anemia or confirms both warm and cold autoimmune components. It is appropriate for confirmed diagnoses in inpatient, outpatient, and specialty hematology records. If the record only says autoimmune hemolytic anemia, you should verify the subtype.

Do not use for

Do not use this code for unspecified hemolytic anemia, hereditary hemolytic disorders, or drug-induced hemolysis. If the autoimmune subtype is not documented, check documentation before assigning D59.13.

Coding tip

Assign this code only when the mixed autoimmune type is explicitly documented; otherwise, query for clarification.

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