ICD-10 Code D57.211 – Sickle-cell/Hb-C disease with acute chest syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.211 – Sickle-cell/Hb-C disease with acute chest syndrome
What it is
D57.211 identifies sickle-cell/Hb-C disease when the patient has acute chest syndrome. Use it for a documented sickling disorder with this specific pulmonary complication.
Clinical signs
Typical findings include chest pain, cough, fever, or shortness of breath in a patient with Hb-C sickle-cell disease. Clinical features vary; refer to documentation.
When to use this code
Use this code when the record clearly states sickle-cell/Hb-C disease and acute chest syndrome together. It is appropriate for inpatient, emergency, or follow-up documentation that names the complication. If the chart only says sickle-cell crisis or chest symptoms, check documentation.
Do not use for
Do not use it for sickle-cell disease without acute chest syndrome, or for other sickle-cell genotypes. Do not assume the diagnosis from chest pain alone.
Coding tip
Code only when the provider links acute chest syndrome to Hb-C sickle-cell disease in the documentation.