ICD-10 Code D59.32 – Hereditary hemolytic-uremic syndrome (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Hereditary hemolytic-uremic syndrome is D59.32.
2026 ICD-10-CM Diagnosis Code D59.32 – Hereditary hemolytic-uremic syndrome

What it is

This code identifies a hereditary form of hemolytic-uremic syndrome, an inherited condition that affects small blood vessels and can cause red blood cell destruction and kidney injury. Use it when the diagnosis is specifically documented as hereditary.

Clinical signs

Clinical features may include hemolytic anemia, low platelet count, and signs of renal involvement such as reduced urine output or edema. Clinical features vary; refer to documentation.

When to use this code

Use D59.32 when the provider documents hereditary hemolytic-uremic syndrome, including inherited atypical HUS or a familial form. You may also use it when the record clearly links the syndrome to a genetic cause. If the chart only says “HUS” without hereditary detail, check documentation.

Do not use for

Do not use this code for acquired hemolytic-uremic syndrome, thrombotic thrombocytopenic purpura, or kidney disease without hemolysis. If the hereditary nature is not documented, do not assume this code.

Coding tip

Confirm the word “hereditary” or an equivalent genetic/familial statement in the provider note before assigning D59.32.

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