ICD-10 Code D57.812 – Other sickle-cell disorders with splenic sequestration (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other sickle-cell disorders with splenic sequestration is D57.812.
2026 ICD-10-CM Diagnosis Code D57.812 – Other sickle-cell disorders with splenic sequestration

What it is

D57.812 identifies sickle-cell disease or a related sickling disorder when the spleen traps blood cells, causing acute enlargement and reduced circulating blood volume. Use it for splenic sequestration specifically, not for uncomplicated sickle-cell disease.

Clinical signs

Typical findings include sudden splenic enlargement, abdominal pain, pallor, weakness, and signs of acute anemia. Clinical features vary; refer to documentation.

When to use this code

Use this code when the record documents splenic sequestration in a patient with an other sickle-cell disorder. It fits encounters where the provider links the spleen-related crisis to the sickling condition. If the note only states sickle-cell disease without sequestration, choose a different code.

Do not use for

Do not use it for splenic sequestration without a documented sickle-cell disorder. Also avoid it when the chart describes a different sickle-cell complication or the diagnosis is unclear; check documentation.

Coding tip

Confirm both elements in the note: the sickle-cell disorder and splenic sequestration.

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