ICD-10 Code D57.80 – Other sickle-cell disorders without crisis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other sickle-cell disorders without crisis is D57.80.
2026 ICD-10-CM Diagnosis Code D57.80 – Other sickle-cell disorders without crisis

What it is

This code identifies sickle-cell disorder that does not fit a more specific subtype and is not currently in crisis. Use it when the record documents a sickling disorder, but no acute vaso-occlusive event is present.

Clinical signs

Clinical features vary; refer to documentation. Patients may have chronic anemia, jaundice, fatigue, or other manifestations of sickle-cell disease, but the chart should not describe an active pain crisis or acute complication.

When to use this code

Use D57.80 when the provider documents an “other” sickle-cell disorder and explicitly states there is no crisis. It also fits follow-up or routine management visits where the condition is present but stable. If the note names a more specific sickle-cell subtype, choose that code instead.

Do not use for

Do not use this code for sickle-cell crisis, acute chest syndrome, or other documented acute complications. If the record supports a more specific sickle-cell diagnosis, code that condition rather than this unspecified category.

Coding tip

Check the provider’s wording carefully: “without crisis” must be documented, and any acute sickle-cell complication should be coded separately when supported.

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