ICD-10 Code D57.434 – Sickle-cell thalassemia beta zero with dactylitis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.434 – Sickle-cell thalassemia beta zero with dactylitis
What it is
D57.434 identifies sickle-cell thalassemia beta zero with dactylitis. Use it when the record documents this inherited hemoglobin disorder and swelling or pain in the fingers or toes consistent with dactylitis.
Clinical signs
Typical findings include painful swelling of the hands or feet, especially in young patients with sickle-cell disease. Clinical features vary; refer to documentation for the confirmed diagnosis and whether dactylitis is present.
When to use this code
Use this code when the provider documents sickle-cell thalassemia beta zero and specifically links the encounter to dactylitis. It is appropriate for visits focused on acute finger or toe swelling in the setting of this hemoglobinopathy. If the note does not specify beta zero or dactylitis, check documentation before assigning this code.
Do not use for
Do not use this code for other sickle-cell variants, uncomplicated sickle-cell thalassemia, or generalized pain without dactylitis. Check documentation if the type of thalassemia is unclear.
Coding tip
Confirm both the specific genotype and the documented dactylitis before coding D57.434.