ICD-10 Code G92.0 – Immune effector cell-associated neurotoxicity syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code G92.0 – Immune effector cell-associated neurotoxicity syndrome
What it is
G92.0 identifies neurotoxicity linked to immune effector cell therapy, such as CAR-T treatment. Use it when the record documents this specific treatment-related neurologic syndrome.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include confusion, aphasia, reduced attention, tremor, or decreased level of consciousness after immune effector cell therapy.
When to use this code
Use G92.0 when the provider documents immune effector cell-associated neurotoxicity syndrome, ICE-associated neurotoxicity, or similar wording tied to the therapy. Code it for neurologic toxicity occurring after immune effector cell treatment when the diagnosis is established in the chart.
Do not use for
Do not use this code for general delirium, encephalopathy, or neurologic symptoms without a documented link to immune effector cell therapy. Check documentation if the cause is unclear.
Coding tip
Capture the exact provider diagnosis and therapy context; this code depends on documented immune effector cell-related neurotoxicity, not just neurologic symptoms.