ICD-10 Code E28.39 – Other primary ovarian failure (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E28.39 – Other primary ovarian failure
What it is
E28.39 identifies primary ovarian failure that is not otherwise specified by a more precise code. Use it for ovarian dysfunction causing reduced or absent ovarian activity when the documentation supports this diagnosis.
Clinical signs
Clinical features vary; refer to documentation. Common findings may include amenorrhea or irregular menses, infertility, and signs of hypoestrogenism, but you should code only when the record supports primary ovarian failure.
When to use this code
Use E28.39 when the clinician documents other primary ovarian failure, premature ovarian insufficiency, or similar terminology without a more specific code. It may appear in fertility evaluations, menstrual disorder workups, or endocrine assessments. Check documentation for the exact diagnosis wording.
Do not use for
Do not use this code for menopause, surgical ovarian removal, or secondary ovarian dysfunction due to pituitary or hypothalamic disease. If the cause is documented elsewhere, code the underlying condition instead.
Coding tip
Match the code to the provider’s exact wording and avoid assuming primary ovarian failure from infertility alone.