ICD-10 Code B00.81 – Herpesviral hepatitis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Herpesviral hepatitis is B00.81.
2026 ICD-10-CM Diagnosis Code B00.81 – Herpesviral hepatitis

What it is

B00.81 identifies hepatitis caused by herpesvirus infection, most often herpes simplex virus. Use it when documentation shows liver inflammation attributed to herpesviral disease.

Clinical signs

Clinical features vary; refer to documentation. Typical findings may include acute hepatitis with abdominal pain, jaundice, elevated liver enzymes, and evidence of herpesvirus infection.

When to use this code

Use this code when the provider documents herpesviral hepatitis, herpes simplex hepatitis, or hepatitis due to herpesvirus. It is appropriate when the liver involvement is clearly linked to the viral infection. Check documentation if the record only notes hepatitis without a stated herpes cause.

Do not use for

Do not use B00.81 for nonspecific viral hepatitis or hepatitis from another identified cause. Also avoid it when herpes infection is present without documented hepatic involvement.

Coding tip

Confirm that the chart links hepatitis to herpesvirus before assigning B00.81.

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