ICD-10 Code G92.01 – Immune effector cell-associated neurotoxicity syndrome, grade 1 (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code G92.01 – Immune effector cell-associated neurotoxicity syndrome, grade 1
What it is
This code identifies grade 1 immune effector cell-associated neurotoxicity syndrome, a mild neurologic complication after immune effector cell therapy. It reflects documented neurotoxicity severity, not the underlying cancer or treatment.
Clinical signs
Clinical features vary; refer to documentation. Grade 1 may include subtle neurologic changes such as mild confusion, attention problems, or reduced handwriting, without severe impairment.
When to use this code
Use this code when the provider documents immune effector cell-associated neurotoxicity syndrome and specifies grade 1. It is appropriate in patients monitored after CAR-T or other immune effector cell therapy when mild neurotoxicity is recorded. If the grade is not stated, check documentation.
Do not use for
Do not use this code for general confusion, delirium, or other neurologic symptoms without a documented diagnosis of immune effector cell-associated neurotoxicity syndrome. Do not assign it when the severity is another grade.
Coding tip
Code the documented grade exactly; if the record does not specify grade 1, query the provider before assigning G92.01.