ICD-10 Code F19.229 – Other psychoactive substance dependence with intoxication, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.229 – Other psychoactive substance dependence with intoxication, unspecified
What it is
Use this code for dependence on a psychoactive substance other than alcohol, nicotine, or a specific named drug, when intoxication is also present and the substance is not further specified. It indicates both dependence and acute intoxication.
Clinical signs
Clinical features vary; refer to documentation. Intoxication may include altered behavior, impaired judgment, mood changes, or decreased coordination, along with evidence of ongoing dependence.
When to use this code
Use F19.229 when the record documents dependence on an unspecified psychoactive substance and the patient is currently intoxicated. Choose it when the provider does not name the drug, but clearly links dependence and intoxication in the assessment.
If the note only describes intoxication, or only dependence without intoxication, this code is not appropriate. Check documentation for the exact substance and whether the intoxication is current.
Do not use for
Do not use this code for alcohol, tobacco, or a specifically identified psychoactive substance with its own ICD-10 category. Do not use it when dependence is documented without intoxication.
Coding tip
Code the substance as unspecified only when the provider truly does not identify it; otherwise, select the more specific code.