ICD-10 Code F19.23 – Other psychoactive substance dependence with withdrawal (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.23 – Other psychoactive substance dependence with withdrawal
What it is
F19.23 identifies dependence on a psychoactive substance not classified elsewhere, with withdrawal symptoms present when use is reduced or stopped. Use this code when the record supports both dependence and withdrawal.
Clinical signs
Clinical features vary; refer to documentation. Typical withdrawal findings may include anxiety, agitation, insomnia, tremor, or other substance-specific symptoms, but you should code only what is documented.
When to use this code
Use F19.23 when the clinician documents dependence on an unspecified or other psychoactive substance and notes withdrawal. This may apply during evaluation, inpatient care, or emergency visits where withdrawal is part of the diagnosis. Make sure the substance is not better classified elsewhere.
Do not use for
Do not use this code for simple use, intoxication, or abuse without dependence and withdrawal. If the substance is known and has a more specific ICD-10 code, use that code instead.
Coding tip
Verify that both dependence and withdrawal are documented before assigning F19.23.