ICD-10 Code F19 – Other psychoactive substance related disorders (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19 – Other psychoactive substance related disorders
What it is
F19 identifies mental and behavioral disorders caused by psychoactive substances other than alcohol, opioids, cannabis, cocaine, or other specifically named drug groups. Use it when documentation shows a substance-related disorder but the exact substance is not one of the more specific codes.
Clinical signs
Clinical features vary; refer to documentation. Records may describe intoxication, withdrawal, dependence, harmful use, or substance-induced psychiatric symptoms linked to an unspecified psychoactive substance.
When to use this code
Use F19 when the clinician documents a disorder related to an unspecified or other psychoactive substance and the record does not support a more specific ICD-10 code. It is also appropriate when the substance class is known to be psychoactive, but the exact agent is not identified. Check documentation for the specific disorder type and any associated mental or behavioral manifestations.
Do not use for
Do not use F19 when the substance is clearly identified as alcohol, opioids, cannabis, cocaine, or another more specific drug category. If the chart lacks enough detail, check documentation rather than guessing.
Coding tip
Code the documented substance-related disorder first, then verify whether a more specific substance code is available before defaulting to F19.