ICD-10 Code F19.121 – Other psychoactive substance abuse with intoxication delirium (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.121 – Other psychoactive substance abuse with intoxication delirium
What it is
This code identifies abuse of another psychoactive substance when intoxication has progressed to delirium. Use it when the substance is not specifically named elsewhere and the record supports both abuse and delirium.
Clinical signs
Delirium usually includes disturbed attention, disorientation, fluctuating awareness, and confused thinking. Clinical features vary; refer to documentation.
When to use this code
Use this code when the provider documents psychoactive substance abuse with intoxication delirium and the substance is not separately classified. It may apply when the chart clearly links the delirium to acute intoxication and describes abuse rather than dependence or use without complication.
Do not use for
Do not use it if the record shows intoxication without delirium, or delirium from another cause. If the substance type, abuse status, or relationship to the delirium is unclear, check documentation.
Coding tip
Verify the provider’s wording for abuse, intoxication, and delirium before assigning F19.121.