ICD-10 Code D59.8 – Other acquired hemolytic anemias (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D59.8 – Other acquired hemolytic anemias
What it is
D59.8 identifies acquired hemolytic anemia caused by red blood cell destruction from an external or later-developing cause, when a more specific hemolytic anemia code does not fit. Use it for documented acquired hemolysis not otherwise classified.
Clinical signs
Clinical features vary; refer to documentation. Common findings may include anemia symptoms, jaundice, dark urine, or laboratory evidence of hemolysis, but the record should support an acquired cause.
When to use this code
Use D59.8 when the provider documents an acquired hemolytic anemia and does not name a more specific subtype. It also fits cases where hemolysis is clearly acquired, but the exact mechanism remains unspecified in the note. Code the documented cause first when that is identified.
Do not use for
Do not use this code for hereditary hemolytic anemias, autoimmune hemolytic anemia with a more specific code, or anemia from blood loss or nutritional deficiency. Check documentation if the chart does not clearly state acquired hemolysis.
Coding tip
Query for the underlying cause and any more specific hemolytic anemia diagnosis before assigning D59.8.