ICD-10 Code E85.0 – Non-neuropathic heredofamilial amyloidosis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E85.0 – Non-neuropathic heredofamilial amyloidosis
What it is
This code identifies a hereditary amyloidosis that does not primarily involve the peripheral nerves. You use it when documentation specifies a familial amyloid disorder with non-neuropathic presentation.
Clinical signs
Clinical features vary; refer to documentation. Standard references describe amyloid deposition with organ involvement, but this code is for cases without primary neuropathic findings.
When to use this code
Use E85.0 when the provider documents non-neuropathic heredofamilial amyloidosis, familial amyloidosis, or a hereditary amyloid disorder with no stated neuropathy. Apply it only when the record clearly distinguishes this subtype. Check documentation if the amyloid type or organ pattern is not specified.
Do not use for
Do not use this code for amyloidosis with primary neuropathic involvement or when the hereditary type is not confirmed. If the chart only says “amyloidosis” without subtype, you need more specific documentation.
Coding tip
Code the documented amyloid subtype exactly as stated, and query the provider when hereditary status or neuropathic involvement is unclear.