ICD-10 Code D57.44 – Sickle-cell thalassemia beta plus without crisis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.44 – Sickle-cell thalassemia beta plus without crisis
What it is
This code identifies sickle-cell beta-plus thalassemia without a current crisis. It describes a hereditary hemoglobin disorder where sickling occurs alongside reduced beta-globin production.
Clinical signs
Clinical features vary; refer to documentation. Common findings may include chronic anemia, fatigue, jaundice, or splenic enlargement, but the record should support the specific diagnosis and absence of crisis.
When to use this code
Use D57.44 when the provider documents sickle-cell thalassemia, beta-plus type, and states the patient is not in crisis. This applies to routine encounters, follow-up visits, and chronic disease management. You should code the documented subtype rather than a broader sickle-cell category.
Do not use for
Do not use this code if the record does not specify beta-plus thalassemia or if a sickle-cell crisis is present. Check documentation for other sickle-cell variants or thalassemia-only diagnoses.
Coding tip
Confirm both the hemoglobin subtype and the “without crisis” status in the provider note before assigning D57.44.