ICD-10 Code D57.04 – Hb-SS disease with dactylitis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.04 – Hb-SS disease with dactylitis
What it is
This code identifies sickle cell anemia (Hb-SS disease) with dactylitis, a painful swelling of the hands or feet caused by vaso-occlusion. Use it when the record links the dactylitis directly to Hb-SS disease.
Clinical signs
Typical findings include acute pain, swelling, and tenderness of the hands or feet in a patient with sickle cell disease. Clinical features vary; refer to documentation.
When to use this code
Use D57.04 when the provider documents Hb-SS disease and states that dactylitis is present, current, or being treated as part of the encounter. It is appropriate for episodes described as hand-foot syndrome in a patient with sickle cell anemia. If the note only mentions sickle cell disease without dactylitis, check documentation before assigning this code.
Do not use for
Do not use this code for dactylitis from another cause or for sickle cell disease without documented dactylitis. Check documentation if the type of sickle cell disorder is not clearly Hb-SS.
Coding tip
Confirm both the Hb-SS diagnosis and the dactylitis in the same record before coding D57.04.