ICD-10 Code D57.00 – Hb-SS disease with crisis, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D57.00 – Hb-SS disease with crisis, unspecified
What it is
This code identifies sickle cell anemia (Hb-SS) with a crisis, but the specific crisis type is not documented. Use it when the record confirms Hb-SS disease and an acute crisis episode.
Clinical signs
Clinical features vary; refer to documentation. Common crisis findings include acute pain, anemia-related symptoms, or other sickle cell complications noted by the provider.
When to use this code
Use D57.00 when the provider documents Hb-SS disease and a crisis, but does not specify the crisis type. It also fits when the note says “sickle cell crisis” without further detail. If the record names a specific crisis, code that more precisely.
Do not use for
Do not use this code for Hb-SS disease without crisis or for other sickle cell genotypes. Check documentation if the encounter describes a specific crisis subtype, such as acute chest syndrome.
Coding tip
Assign the most specific sickle cell crisis code supported by the chart; use D57.00 only when the crisis type remains unspecified.