ICD-10 Code F19.97 – Other Psychoactive Substance Use, Unspecified with Psychoactive Substance-Induced Persisting Dementia (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance use, unspecified with psychoactive substance-induced persisting dementia is F19.97.
2026 ICD-10-CM Diagnosis Code F19.97 – Other psychoactive substance use, unspecified with psychoactive substance-induced persisting dementia

What it is

This code identifies persisting dementia caused by use of an unspecified psychoactive substance. Use it when the record links ongoing cognitive decline to that substance exposure.

Clinical signs

Clinical features may include memory loss, impaired judgment, disorientation, and reduced ability to perform daily tasks. Clinical features vary; refer to documentation.

When to use this code

Use F19.97 when the provider documents a persisting dementia syndrome due to an unspecified psychoactive substance. It fits cases where cognitive impairment continues after intoxication or withdrawal has ended and the substance type is not named. Check documentation if the record only says substance use disorder or acute intoxication.

Do not use for

Do not use this code for acute intoxication, withdrawal, or transient delirium without persisting dementia. Also avoid it when the substance is specifically identified and a more precise code is documented.

Coding tip

Confirm both the dementia diagnosis and the causal substance link in the provider note before assigning F19.97.

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