ICD-10 Code F19.25 – Other psychoactive substance dependence with psychoactive substance-induced psychotic disorder (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.25 – Other psychoactive substance dependence with psychoactive substance-induced psychotic disorder
What it is
Use this code for dependence on another psychoactive substance when the patient also has a psychotic disorder caused by that substance. It identifies both the substance use disorder and the substance-induced psychosis.
Clinical signs
Clinical features vary; refer to documentation. Typical findings may include delusions, hallucinations, disorganized thinking, or marked behavioral disturbance occurring in the setting of substance use.
When to use this code
Use F19.25 when the record clearly links dependence on an unspecified or other psychoactive substance with a substance-induced psychotic disorder. You should code it when the provider documents both conditions together. Check documentation if the substance, timing, or causal relationship is unclear.
Do not use for
Do not use this code for psychosis unrelated to substance use, or for substance use without dependence. If the documentation does not support a psychotic disorder caused by the substance, choose a different code.
Coding tip
Verify that the psychotic disorder is documented as substance-induced and tied to the same psychoactive substance dependence.