ICD-10 Code E71.548 – Other Peroxisomal Disorders (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E71.548 – Other peroxisomal disorders
What it is
E71.548 identifies peroxisomal disorders that do not fit a more specific ICD-10-CM diagnosis. These are inherited metabolic conditions involving abnormal peroxisome function, so use the code only when documentation supports this broader category.
Clinical signs
Clinical features vary; refer to documentation. Findings may include developmental delay, neurologic abnormalities, vision or hearing problems, and liver involvement, depending on the specific peroxisomal disorder.
When to use this code
Use E71.548 when the clinician documents a peroxisomal disorder and no more specific code is available in the record. It is appropriate for confirmed inherited peroxisomal disease that is not otherwise classified. If the note names a specific syndrome or disorder, code that diagnosis instead.
Do not use for
Do not use this code for a more specific peroxisomal diagnosis already documented, or for nonspecific metabolic symptoms alone. Check documentation if the record only says “rule out” or “suspected” disorder.
Coding tip
Confirm the exact disorder name in the chart before assigning this unspecified peroxisomal category.