ICD-10 Code F19.220 – Other psychoactive substance dependence with intoxication, uncomplicated (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.220 – Other psychoactive substance dependence with intoxication, uncomplicated
What it is
This code identifies dependence on another psychoactive substance with current intoxication, without complications. Use it when the substance is not one of the specifically indexed drug classes and the record documents intoxication.
Clinical signs
Intoxication may include altered mood, behavior, judgment, or coordination after substance use. Clinical features vary; refer to documentation, and confirm that dependence is also documented.
When to use this code
Use this code when the provider documents both dependence and intoxication from an unspecified or other psychoactive substance. It fits encounters where the intoxication is uncomplicated and no additional intoxication-related complication is recorded. Check documentation if the substance class is unclear.
Do not use for
Do not use it for simple use, abuse, or dependence without intoxication. Do not assign it when the record identifies a more specific substance code or when complications of intoxication are documented.
Coding tip
Verify that dependence and intoxication are both stated in the note before assigning F19.220.