ICD-10 Code E27.5 – Adrenomedullary hyperfunction (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E27.5 – Adrenomedullary hyperfunction
What it is
This code identifies excess hormone activity from the adrenal medulla, the inner part of the adrenal gland. Use it when the record documents adrenomedullary hyperfunction, such as catecholamine overproduction, without a more specific diagnosis.
Clinical signs
Clinical features vary; refer to documentation. Commonly noted findings may include episodes of palpitations, sweating, headache, or hypertension when the underlying cause is catecholamine excess.
When to use this code
Use E27.5 when the provider specifically documents adrenomedullary hyperfunction or a similar term and does not name a more precise condition. It may also fit when the chart describes adrenal medulla overactivity that is being evaluated or monitored. Check documentation if the note instead identifies a tumor or another endocrine disorder.
Do not use for
Do not use this code for general adrenal disorders, adrenal cortical problems, or unspecified hypertension alone. If the record names a different adrenal mass or endocrine diagnosis, code that condition instead.
Coding tip
Query the provider when the note suggests catecholamine excess but does not clearly state adrenomedullary hyperfunction.