ICD-10 Code E27.40 – Unspecified adrenocortical insufficiency (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E27.40 – Unspecified adrenocortical insufficiency
What it is
This code identifies adrenal cortex insufficiency when the record does not specify the cause or type. It indicates inadequate adrenal hormone production, but the documentation is not detailed enough for a more specific code.
Clinical signs
Clinical features vary; refer to documentation. Commonly noted findings may include fatigue, weakness, weight loss, low blood pressure, or other signs of adrenal hormone deficiency.
When to use this code
Use E27.40 when the provider documents adrenocortical insufficiency without identifying whether it is primary, secondary, or due to another cause. It also fits when the chart confirms adrenal insufficiency but lacks enough detail for a more specific code. Check documentation before defaulting to unspecified coding.
Do not use for
Do not use this code if the record specifies a more exact adrenal disorder, such as primary or secondary adrenal insufficiency. It is also not for nonspecific symptoms alone without a documented diagnosis.
Coding tip
Query the provider when the note says “adrenal insufficiency” but does not state the type or cause.