ICD-10 Code C94.40 – Acute panmyelosis with myelofibrosis not having achieved remission (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C94.40 – Acute panmyelosis with myelofibrosis not having achieved remission
What it is
C94.40 identifies acute panmyelosis with myelofibrosis when the condition is present and remission has not been achieved. It describes a rare acute myeloid neoplasm involving the bone marrow and fibrosis.
Clinical signs
Clinical features vary; refer to documentation. Typical records may note marrow failure, anemia, thrombocytopenia, leukopenia, and evidence of myelofibrosis on pathology or hematology evaluation.
When to use this code
Use this code when the provider documents acute panmyelosis with myelofibrosis and specifies that remission has not been achieved. It is appropriate for active disease, including initial diagnosis or persistent disease after prior therapy. Check documentation if remission status is unclear.
Do not use for
Do not use it for myelofibrosis without acute panmyelosis, or for other leukemias unless this diagnosis is explicitly stated. If the record says remission achieved, select the remission code instead.
Coding tip
Code only when both the diagnosis and the “not having achieved remission” status are documented.