ICD-10 Code C94.2 – Acute megakaryoblastic leukemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C94.2 – Acute megakaryoblastic leukemia
What it is
Acute megakaryoblastic leukemia is a rare acute leukemia involving immature megakaryoblasts, the cells that normally develop into platelets. Use this code when documentation specifically identifies this subtype.
Clinical signs
Clinical features vary; refer to documentation. Common findings in acute leukemia include fatigue, infection, bruising, bleeding, anemia, and evidence of bone marrow replacement by blasts.
When to use this code
Use C94.2 when the provider documents acute megakaryoblastic leukemia, megakaryoblastic leukemia, or an equivalent confirmed diagnosis. It is appropriate for encounters focused on diagnosis, monitoring, or management of this specific leukemia. Check documentation if the leukemia type is not clearly stated.
Do not use for
Do not use this code for other acute myeloid leukemias, chronic leukemias, or nonspecific “leukemia” without subtype confirmation. If the record only says suspected leukemia, check documentation.
Coding tip
Assign C94.2 only when the subtype is explicitly documented; otherwise query for clarification.