ICD-10 Code C81.1 – Nodular sclerosis Hodgkin lymphoma (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C81.1 – Nodular sclerosis Hodgkin lymphoma
What it is
C81.1 identifies nodular sclerosis Hodgkin lymphoma, a subtype of Hodgkin lymphoma. Use it when documentation specifies this histologic form, often involving lymph nodes and a characteristic nodular pattern.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include painless lymphadenopathy and possible “B symptoms” such as fever, night sweats, or weight loss.
When to use this code
Use C81.1 when the provider documents nodular sclerosis Hodgkin lymphoma as the confirmed diagnosis. It also applies when pathology or oncology notes clearly identify this subtype. If the record only says Hodgkin lymphoma without subtype, check documentation before assigning this code.
Do not use for
Do not use this code for other Hodgkin lymphoma subtypes, mixed cellularity disease, or non-Hodgkin lymphomas. If the subtype is unspecified, do not assume nodular sclerosis; check documentation.
Coding tip
Code the exact lymphoma subtype from pathology or oncology documentation, and confirm whether the diagnosis is confirmed, suspected, or ruled out.