ICD-10 Code B45.9 – Cryptococcosis, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Cryptococcosis, unspecified is B45.9.
2026 ICD-10-CM Diagnosis Code B45.9 – Cryptococcosis, unspecified

What it is

B45.9 identifies cryptococcosis when the record confirms infection but does not specify the site or form. Use it for documented cryptococcal disease without a more precise subtype.

Clinical signs

Clinical features vary; refer to documentation. Cryptococcosis may present with pulmonary findings, neurologic symptoms, or disseminated infection, but you should code only what is explicitly documented.

When to use this code

Use B45.9 when the clinician documents cryptococcosis and does not identify a specific manifestation, such as meningitis, pneumonia, or skin involvement. It also fits when the chart confirms cryptococcal infection but the site remains unspecified. If a more detailed diagnosis appears elsewhere in the record, code that instead.

Do not use for

Do not use this code for a specified cryptococcal condition, such as cryptococcal meningitis or pulmonary cryptococcosis. Do not use it when documentation is unclear; check documentation.

Coding tip

Query the provider if the note mentions cryptococcosis but omits the affected site, because a more specific code may be available.

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