ICD-10 Code F11.921 – Opioid use, unspecified with intoxication delirium (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F11.921 – Opioid use, unspecified with intoxication delirium
What it is
This code identifies opioid use with intoxication delirium when the opioid is not further specified. It means the patient has delirium caused by opioid intoxication, with confusion or disturbed awareness linked to recent opioid use.
Clinical signs
Clinical features may include altered attention, disorientation, impaired awareness, and fluctuating mental status. Refer to documentation for evidence that the delirium is attributed to opioid intoxication rather than another cause.
When to use this code
Use this code when the record clearly states opioid intoxication delirium and the opioid is not named more specifically. It may apply in emergency, inpatient, or consult notes when delirium is documented as due to opioid use. If the substance, intent, or delirium cause is unclear, check documentation.
Do not use for
Do not use it for opioid dependence or abuse without delirium, or for opioid intoxication without a delirium diagnosis. Do not assign it when another medical, metabolic, or neurologic cause explains the delirium.
Coding tip
Confirm both opioid use and delirium are documented, and make sure the intoxication link is explicit before assigning F11.921.