ICD-10 Code B46 – Zygomycosis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Zygomycosis is B46.
2026 ICD-10-CM Diagnosis Code B46 – Zygomycosis

What it is

B46 identifies zygomycosis, also called mucormycosis, a serious fungal infection caused by molds in the order Mucorales. Use it when documentation names this infection or a specific form within it.

Clinical signs

Clinical features vary; refer to documentation. Commonly reported findings include rapidly progressive tissue infection, sinus or nasal involvement, pulmonary disease, or invasive infection in immunocompromised patients.

When to use this code

Use B46 when the provider documents zygomycosis or mucormycosis as the diagnosis. It may apply to rhinocerebral, pulmonary, cutaneous, or disseminated infection if the record supports the fungal etiology.

If the note only describes a suspected fungal infection, check documentation before coding. Confirm that the infection is specifically identified as zygomycosis rather than another mycosis.

Do not use for

Do not use B46 for nonspecific fungal infection or for a different organism without documentation. If the chart does not clearly identify zygomycosis, check documentation.

Coding tip

Code B46 only when the provider explicitly links the infection to zygomycosis or mucormycosis.

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