ICD-10 Code F19.280 – Other psychoactive substance dependence with psychoactive substance-induced anxiety disorder (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.280 – Other psychoactive substance dependence with psychoactive substance-induced anxiety disorder
What it is
This code identifies dependence on another psychoactive substance, with anxiety caused by that substance. Use it when the anxiety disorder is documented as substance-induced and linked to the dependence.
Clinical signs
Clinical features vary; refer to documentation. Typical notes may describe anxiety, panic, restlessness, or excessive worry occurring in the context of ongoing substance dependence and not better explained by another primary anxiety disorder.
When to use this code
Use this code when the record clearly states both psychoactive substance dependence and a substance-induced anxiety disorder due to that same substance. It applies when the clinician documents anxiety as caused by the substance rather than a separate mental health diagnosis. Check documentation if the substance is not specified.
Do not use for
Do not use this code for uncomplicated substance dependence without anxiety, or for primary anxiety disorders unrelated to substance use. If the anxiety is not documented as substance-induced, choose the more appropriate anxiety code.
Coding tip
Confirm the causal link between the substance and anxiety in the note before assigning F19.280.