ICD-10 Code F19.28 – Other psychoactive substance dependence with other psychoactive substance-induced disorders (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.28 – Other psychoactive substance dependence with other psychoactive substance-induced disorders
What it is
This code identifies dependence on a psychoactive substance, along with a separate disorder caused by that substance. Use it when the record shows both ongoing dependence and a substance-induced condition.
Clinical signs
Clinical features vary; refer to documentation. You may see evidence of dependence plus symptoms linked to intoxication, withdrawal, mood change, psychosis, or other substance-induced effects.
When to use this code
Use this code when the provider documents dependence on another psychoactive substance and also documents a substance-induced disorder. It fits cases where the induced condition is clinically recognized and tied to the same substance. Check documentation if the specific induced disorder is not clearly stated.
Do not use for
Do not use this code for simple use, abuse, or dependence without a documented substance-induced disorder. Do not assign it when the induced condition is caused by a different substance or when documentation is unclear.
Coding tip
Code both elements only when the record supports dependence and a linked psychoactive substance-induced disorder.