ICD-10 Code F19.27 – Other psychoactive substance dependence with psychoactive substance-induced persisting dementia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.27 – Other psychoactive substance dependence with psychoactive substance-induced persisting dementia
What it is
This code describes dependence on another psychoactive substance with lasting dementia caused by that substance. Use it when documentation links ongoing cognitive decline to the substance effect.
Clinical signs
Findings may include memory loss, impaired judgment, reduced attention, and difficulty with daily function. Clinical features vary; refer to documentation for evidence of persisting dementia and substance dependence.
When to use this code
Use this code when the record states both psychoactive substance dependence and a persisting dementia due to that substance. It fits cases where cognitive impairment remains after intoxication or withdrawal has resolved. Check documentation for the specific substance if it is named.
Do not use for
Do not use it for acute intoxication, withdrawal, or substance use without dependence. Do not assign it if dementia is due to another cause or if the record does not link the dementia to the substance.
Coding tip
Verify that the provider documents both dependence and substance-induced persisting dementia before you code F19.27.