ICD-10 Code F10.221 – Alcohol dependence with intoxication delirium (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Alcohol dependence with intoxication delirium is F10.221.
2026 ICD-10-CM Diagnosis Code F10.221 – Alcohol dependence with intoxication delirium

What it is

F10.221 identifies alcohol dependence with a delirium episode occurring during intoxication. Use it when the record shows both alcohol dependence and an acute confusional state linked to recent alcohol use.

Clinical signs

Clinical features vary; refer to documentation. Delirium typically includes impaired attention, disorientation, fluctuating awareness, and disturbed thinking, with evidence that alcohol intoxication is the associated cause.

When to use this code

Use this code when the provider documents alcohol dependence and specifically states intoxication delirium. It fits encounters where the delirium is attributed to alcohol intoxication rather than withdrawal or another medical condition. If the chart does not clearly link the delirium to intoxication, check documentation.

Do not use for

Do not use for alcohol intoxication without delirium, or for delirium caused by withdrawal, another substance, or a general medical condition. Check documentation if the mental status change is not clearly tied to alcohol intoxication.

Coding tip

Code the dependence and the intoxication delirium together only when the provider explicitly documents both.

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