ICD-10 Code F19.222 – Other psychoactive substance dependence with intoxication with perceptual disturbance (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F19.222 – Other psychoactive substance dependence with intoxication with perceptual disturbance
What it is
Use this code for dependence on a psychoactive substance other than alcohol, nicotine, or a specifically named drug, when intoxication is present with perceptual disturbance. It captures both the dependence and the acute intoxication state.
Clinical signs
Typical findings include recent substance use, impaired judgment, and altered perception such as hallucinations or misperceptions. Clinical features vary; refer to documentation.
When to use this code
Assign this code when the record documents dependence plus intoxication with perceptual disturbance from an unspecified psychoactive substance. Use it for encounters where the clinician links the perceptual changes to intoxication, not to a primary psychotic disorder. Check documentation if the substance is named more specifically elsewhere.
Do not use for
Do not use this code for simple dependence without intoxication or without perceptual disturbance. Do not use it when the substance is identified by a more specific ICD-10 code or when symptoms are better explained by another diagnosis.
Coding tip
Confirm both dependence and intoxication are documented, and code the substance as specifically as the record allows.