ICD-10 Code D89.810 – Acute graft-versus-host disease (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D89.810 – Acute graft-versus-host disease
What it is
Acute graft-versus-host disease is a complication after allogeneic stem cell or bone marrow transplant, when donor immune cells attack the recipient’s tissues. Code D89.810 identifies the acute form.
Clinical signs
Clinical features vary; refer to documentation. Commonly documented findings include skin rash, gastrointestinal symptoms, and liver involvement after transplant, with onset consistent with an acute post-transplant reaction.
When to use this code
Use this code when the provider documents acute graft-versus-host disease, acute GVHD, or an acute post-transplant GVHD diagnosis. It may appear in transplant follow-up, inpatient complication notes, or consults describing active disease. Check documentation for acute versus chronic type.
Do not use for
Do not use this code for chronic graft-versus-host disease or for nonspecific post-transplant symptoms without a documented GVHD diagnosis. Check documentation if the record does not clearly identify the condition.
Coding tip
Verify that the note states “acute” GVHD, because the chronic form uses a different code.