ICD-10 Code D68.59 – Other primary thrombophilia (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other primary thrombophilia is D68.59.
2026 ICD-10-CM Diagnosis Code D68.59 – Other primary thrombophilia

What it is

D68.59 identifies an inherited or otherwise primary tendency to form abnormal blood clots that does not fit a more specific thrombophilia code. Use it when documentation supports a primary clotting disorder, but the exact type is not named.

Clinical signs

Clinical features vary; refer to documentation. Common clues include a personal or family history of unexplained venous thromboembolism, recurrent clots, or thrombosis at a young age without a clear provoking factor.

When to use this code

Use this code when the record states primary thrombophilia, thrombophilia NOS, or another inherited hypercoagulable state that is not otherwise specified. It may also apply when the clinician documents a clotting disorder as the reason for evaluation or long-term risk assessment. Check documentation if an acquired cause is also present.

Do not use for

Do not use this code for acquired hypercoagulable states, such as those related to malignancy, pregnancy, medications, or antiphospholipid syndrome, unless documentation specifically supports a primary disorder. Do not use a more specific thrombophilia code when one is documented.

Coding tip

Code D68.59 only when the provider clearly documents a primary thrombophilia; otherwise, query for specificity.

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